A series of hybridoma cell lines producing antibodies with reactivity to alpha1-antitrypsin, group specific component and phosphoglucomutase-1 are now available in the the ECACC Hybridoma Collection. These hybridoma lines were deposited by Dr. Koen Verhoef of MRC Technology, London, UK.
| Cell Line Name | ECACC no. | Reactivitiy | | 10(AAT) Clone A | 02043015 | Anti- alpha 1 antitrypsin (also kinown as alpha1-T or AAT) |
6G5(AAT)
Clone4D4 | 02043017 | Anti- alpha 1 antitrypsin (also kinown as alpha1-T or AAT) |
| Cell Line Name | ECACC no. | Reactivitiy | | 4H8(GC) Clone 4D4 | 02043019 | Anti- group specific component (GC) |
| Cell Line Name | ECACC no. | Reactivitiy | | 6H7(PGM1) Clone D10 | 02043022 | Anti- phosphoglucomutase-1 (PGM1) |
Group-specific component (GC) is a plasma protein that binds vitamin D. The protein alpha-1 antitrypsin (AAT) is a protease inhibitor. The enzyme phosphoglucomutase-1 (PGM1) participates in both the breakdown and synthesis of glucose. PGM1 connects glycolysis and glycogen metabolism by interconverting glucose-1-phosphate and glucose-6-phosphate.
|
