The underlying cause of all genetic diseases has proved to be a difficult task due to the diversity of genetic and environmental factors that contribute to the disease state. Millions of DNA sequence variants associated with genetic diversity can now potentially be examined due to the identification of the human genome sequence. The most widespread type of DNA variant in the human genome are single nucleotide polymorphisms, (SNPs), which account for diversity in the population, individuality, susceptibility to diseases as well as the response of an individual to medication. SNP’s are identified by association studies, a powerful method that finds allele frequencies of genes from a population with a specific trait or disease and compares them to a control population not selected for any particular phenotype.

Alleles conveying disease susceptibility are identified and verified by comparing with control, non disease alleles. However some scientists are facing difficulties obtaining sufficient numbers of blood samples to statistically substantiate their genetic and clinical data. At ECACC we have developed a product that can help you achieve this task. Our scientists have extracted high quality purified DNA from cell lines generated from apparently healthy randomly selected individuals. This cell line DNA can be used as reference standards in route assays, for the development and validation of new assays and for investigating the genetic basis of specific diseases.

Benefits include:

• Standardisation
• Authentication
• Highly purified with high molecular weight
• Ready to use
• Immediate availability
• Convenient formats
• Cost effective

The DNA panels now  available to purchase include:

• Human Random Control (HRC) panels
• Ethnic Diversity DNA panels
• Genetic Disease DNA panels

For full details on each one click on the relevant category from the menu selection on the left and contact our technical specialist for further information.