Following the publication of the draft sequence of the human genome in the year 2000, the MRC made awards to enable collections of large numbers of samples for thirteen common disorders of major public health significance. It was anticipated that these thirteen collections would form the basis of a national resource that should be managed centrally to ensure availability for future research. Consequently, the MRC also funded a central DNA banking initiative that has evolved into the UK DNA Banking Network (UDBN)
UDBN is a partnership between investigators and infrastructure providers. Its primary aim is to facilitate investigation of the genetics of high impact diseases. To achieve this, UDBN:
- harmonises and standardises sample and data management for numerous disease-based studies
- provides tools that assist in creating collaborations between study investigators and other scientists in the UK and overseas.
Go to www.dna-network.ac.uk to access data on subject phenotypes and on the availability of the corresponding DNA and cells. Then use UDBN's collaboration management system to initiate the right collaboration for you.
Investigators in the UDBN partnership hold samples at ECACC (for cell lines and peripheral blood lymphocyte samples) and the University of Manchester's Centre for Integrated Genome Research (for DNA samples).
ECACC holds cell lines and peripheral blood lymphocyte samples from UDBN partners studying the following disorders:
| Disease | Principal Investigators | Affiliation | | Asthma & Eczema | Prof. W Cookson | Imperial College London (formerly Wellcome Trust Centre for Human Genetics,Oxford) | | Breast Cancer (Sib pairs) | Prof. E. Solomon | King’s College London | | Coronary Heart Disease | Prof. A Hall Prof. N J Samani | University of Leeds University of Leicester | | Glomerulonephritis | Prof. A Rees | University of Aberdeen | | Hypertension | Prof. M Caulfield | St Barts & Royal London | | Late onset Alzheimer’s disease | Prof. J WIlliams | University of Wales: Cardiff | | Multiple Sclerosis | Prof. A Compston | University of Cambridge | | Type 2 Diabetes | Prof. A Hattersley | University of Exeter | | Unipolar Depression | Prof. P McGuffin | Institute of Psychiatry, London |
If you already have a collection stored at ECACC, or are contemplating initiating a new study involving the collection of large numbers of samples for genetic analysis, and are interested in adding value to your study by making material and data available to other researchers through the UDBN collaboration management system contact Dr Pippa Bracegirdle on +44 (0) 1980 612684 or e-mail [email protected]
|
