ECACC announces that Sigma-Aldrich and Dainippon Sumitomo Pharmaceutical Co are the official distributors of ECACC's Human Random Control (HRC) DNA panels. This agreement extends ECACC's market reach and will bring our exclusive HRC DNA panels to a vastly increased number of researchers worldwide. A number of academic research institutes and major pharmaceutical / biotechnology companies are using our HRC panels in key research studies: - Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits
MacDermot et al: American Journal of Human genetic, 2005, Vol 76, 1074 A genome annotation-driven approach to cloning the human ORFeome Collin et al: Genome Biology, 2004, vol 5, R84 The impact of SNP density on fine-scale patterns of linkage disequilibrium Ke et al: Human Molecular Genetics, 2004, Vol. 13, 577-588 An association between variants in the IGF2 gene and Beckwith-Wiedemann syndrome: interaction between genotype and epigenotype Murrell et al: Human Molecular Genetics, 2004, Vol 13, 247-255 The range of HRC DNA samples represents a control population of 480 UK Caucasian blood donors. The HRC DNA is extracted from Epstein Barr Virus immortalised lymphoblastoid cell lines, that can be continously propagated in culture. This ensures an infinite supply of the standardised DNA panels. The purified HRC DNA is available in 5 different panels (HRC-1 through to 5) each consisting of samples from 96 individuals with 10mg each at a concentration of 200 ng/ml. For convenience, two of the panels (HRC-1 and HRC-2) are available as a 96 well format for use in PCR at a concentration of 8 ng/ml, this removes the need for aliquoting or dilution The format of the HRC DNA panels enables the panels to be used in high throughput assimiliation of genomic data for target prioritisation and microarray analysis.
|
| Order HRC DNA through Dainippon Sumitomo Pharmaceutical Co.  |