General Cell Collection
ECACC No.
06070401
Cell Line Name
REM 885
Keywords
Human EBV transformed lymphocytes Alzheimers
Cell Line Description
Derived from a patient with early onset Alzheimers disease and cerebral amyloid angiopathy (CAA), carrying a microduplication of the APP gene locus on chromosome 21. This is an EBV-transformed lymphoblastoid cell line.
Species
Human
Tissue
Lymphocyte
Morphology
Lymphoblastoid
Passage Number
5
Sub Culture Routine
Maintain cultures between 300,000 to 900,000 cells/ml; 5% CO2; 37°C
Culture Medium
RPMI 1640 + 2mM Glutamine + 20% Foetal Bovine Serum (FBS).
Karyotype
46XY
Depositor
Dr N Lemeur, EFS, Laboratoire de Cytogenetique, 605 Chemin de la Breteque, BP 558, Boisguillaume 76235, France & Dr. Dominique Campion, INSERM U614 Faculte de Medecine 22 Boulevard Gambetta 76183 Rouen Cedex 1 France
Originator
Yes
Country
France
References
Rovelet-Lecrux et al: APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet 2006, 38(1):24-26.
Additional Literature Report
Not Available
Additional Bibliography
Research Council Deposit
No
Release Conditions
DNA Available from Stock
The ECACC collections represent deposits of cell cultures from world-wide sources. While every effort is made to ensure details distributed by ECACC are accurate, ECACC cannot be held responsible for any inaccuracies in the data supplied. References where quoted are mainly attributed to the establishment of the cell culture and not for any specific property of the cell line, therefore further references should be obtained regarding cell culture characteristics. Passage numbers where given act only as a guide and ECACC does not guarantee the passage number stated will be the passage number received by the customer. Cell lines supplied by ECACC are for research purposes only. Enquiries regarding the commercial use of a cell line are referred to the depositor of the cell line. Some cell lines have additional special release conditions such as the requirement for a material transfer agreement to be completed by the potential recipient prior to the supply of the cell line. Please view the ECACC Terms & Conditions of Supply for more information.
Delivery State
Frozen -
£295.00
Growing -
£365.00
DNA -
See Price List and manual Order Form.
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